发明名称 |
Gridlock nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
摘要 |
The invention provides a novel gene, gridlock, and its encoded protein. gridlock plays a role in vascular development and modeling, and a mutation in gridlock has been associated with an aortic arch disease, coarctation. Thus, gridlock nucleic acid molecules and polypeptides can be used in methods of diagnosing, treating, and preventing gridlock-related diseases and conditions, such as aortic arch diseases.
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申请公布号 |
US6991936(B2) |
申请公布日期 |
2006.01.31 |
申请号 |
US20030364012 |
申请日期 |
2003.02.10 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
FISHMAN MARK C.;ZHONG TAO P. |
分类号 |
A01K67/027;C12N1/00;A61K31/7088;A61K35/12;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P9/00;A61P9/10;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12N15/09;C12N15/63;C12N15/70;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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