发明名称 Modulators of peroxisome proliferator activated receptors
摘要 Compounds represented by Formula (I) are disclosed. These compounds are useful in the preparation of a medicament for the modulation of a peroxisome proliferators activated receptor (PPAR). Methods of preparing the described compounds are also disclosed. A method of determining whether a compound does or does not interact directly with peroxisome proliferator-activated receptor, comprising the step of specifically binding a radiolabeled compound of formula (I) to the ligand binding domain of the peroxisome proliferators -activated receptor, is also described.
申请公布号 NZ529351(A) 申请公布日期 2006.01.27
申请号 NZ20020529351 申请日期 2002.05.30
申请人 ELI LILLY AND COMPANY;LIGAND PHARMACEUTICALS, INC 发明人 BROOKS, DAWN ALISA;WARSHAWSKY, ALAN M;MONTROSE-RAFEZADEH, CHAHRZAD;REIFEL-MILLER, ANNE;PRIETO, LOURDES;ROJO, ISABEL;MARTIN, JOSE ALFREDO;GONZALES GARCIA, MARIA ROSARIO;TORRADO, ALICIA;FERRITTO CRESPO, RAFAEL;LAMAS-PETEIRA, CARLOS;MARTIN-ORTEGA FINGER, MARIA;ARDECKY, ROBERT J
分类号 C07D295/08;A61K31/19;A61K31/275;A61K31/343;A61K31/352;A61K31/353;A61K31/36;A61K31/381;A61K31/40;A61K31/4035;A61K31/404;A61K31/41;A61K31/4164;A61K31/428;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4453;A61K31/47;A61K31/472;A61K31/495;A61K31/5375;A61K45/00;A61P1/14;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/04;A61P9/12;A61P15/00;C07B61/00;C07C51/09;C07C59/68;C07C59/72;C07C59/90;C07C213/08;C07C217/20;C07C217/84;C07C217/92;C07C219/10;C07C233/25;C07C233/29;C07C233/60;C07C233/75;C07C235/56;C07C235/64;C07C239/12;C07C251/48;C07C255/54;C07D209/08;C07D209/48;C07D213/30;C07D213/64;C07D213/82;C07D215/12;C07D215/14;C07D217/02;C07D233/60;C07D257/04;C07D277/64;C07D295/096;C07D295/10;C07D295/112;C07D295/185;C07D307/79;C07D307/83;C07D307/91;C07D307/93;C07D311/30;C07D311/32;C07D317/20;C07D317/22;C07D317/54;C07D317/64;C07D333/16;C07D333/76;C07D335/02;C07D521/00;C07F7/18;(IPC1-7):C07C59/68;C07C217/94;A61K31/192;A61K31/195 主分类号 C07D295/08
代理机构 代理人
主权项
地址