| 发明名称 |
CRYSTAL OF PDE5, ITS CRYSTAL STRUCTURE AND ITS USE IN DRUG DESIGN. |
| 摘要 |
<p>The present invention relates to the soakable crystals of a phosphodiesterase 5 (PDE5) and their uses in identifying PDE5 ligands, including PDE5 ligands and inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. The present invention additionally relates to crystals of PDE5 into which ligands may be soaked and crystals of PDE5 10 comprising PDE5 ligands that have been soaked into the crystal.</p> |
| 申请公布号 |
MXPA05011769(A) |
申请公布日期 |
2006.01.26 |
| 申请号 |
MX2005PA11769 |
申请日期 |
2004.04.21 |
| 申请人 |
PFIZER INC. |
发明人 |
WENDY ELAINE TAYLOR |
| 分类号 |
A61K31/00;C12N9/16;G01N33/68;(IPC1-7):A61K31/00 |
主分类号 |
A61K31/00 |
| 代理机构 |
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