摘要 |
The present invention relates to a method of treatment of hot flushes with a 5-HT<SUB>2C </SUB>receptor agonist and in particular to the use of the selective 5-HT<SUB>2C </SUB>receptor agonists 1 -[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine and (S)-(+)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy-pyrrolidine or pharmaceutically acceptable acid addition salts thereof for the manufacture of a pharmaceutical formulation adapted for the treatment of hot flushes.
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