| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for detecting base polymorphism clearly and simply, capable of obtaining a result rapidly and easily in a good reproducibility, since without requiring complex operations. SOLUTION: This method for detecting the base polymorphism by performing an amplifying reaction by using an oligonucleotide in a specimen solution containing a specific nucleic acid sequence and at the same time with or after the amplification reaction, bringing the oligonucleotide bonded with a first ligand specifically bonding with the nucleic acid sequence in contact with an oligonucleotide specifically recognizing the base polymorphic zone bonded with a second ligand is provided by using a solid carrier bonded with a capturing agent bonding with the first ligand and a physiologically active substance bonding with the second ligand. COPYRIGHT: (C)2006,JPO&NCIPI
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