Methods of increasing the production of cobalamins using cob gene expression

摘要

Novel polypeptides involved in the biosynthesis of cobalamines and/or cobamides, in particular coenzyme B₁₂, genetic material responsible for expressing these polypeptides, and a method for preparing them, are described. A method for amplifying the production of cobalamines, and particularly coenzyme B₁₂, using recombinant DNA techniques, are also described.