发明名称 |
Activation induced deaminase (AID) |
摘要 |
The present invention identifies that the expression of Activation Induced Deaminase (AID) or its homologues in cells confers a mutator phenotype and thus provides a method for generating diversity in a gene or gene product as well as cell lines capable of generating diversity in defined gene products. The invention also provides methods of modulating a mutator phenotype by modulating AID expression or activity.
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申请公布号 |
US2006019262(A1) |
申请公布日期 |
2006.01.26 |
申请号 |
US20040985321 |
申请日期 |
2004.11.10 |
申请人 |
MEDICAL RESEARCH COUNCIL |
发明人 |
PETERSEN-MAHRT SVEND K.;HARRIS REUBEN;NEUBERGER MICHAEL S.;BEALE RUPERT CHRISTOPHER L. |
分类号 |
C12Q1/68;C07H21/04;C12N1/21;C12N9/78;C12N9/80;C12P21/06 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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