摘要 |
The invention relates to a method of selecting a mammal having or suspected of having a tumour for treatment with an erbB receptor drug which comprises testing a biological sample from the mammal for expression of any one of the genes listed in Table 1 or 2 as defined herein whereby to predict an increased likelihood of response to the erbB receptor drug. Preferred genes include any one of NES, GSPT2, ETR101, TAZ, CHST7, DNAJC3, NPAS2, PIN1, TCEA2, VAMP4, DAPK1, DAPK2, MLLT3, TNNC1, KIAA0931, ACOX2, EMP1, SLC20A1, SPRY2 or PGM1. |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;HUDSON, KEVIN;SOUTH, MARIE, CAROLINE;MARSHALL, GAYLE;SAM, MEHRAN |
发明人 |
HUDSON, KEVIN;SOUTH, MARIE, CAROLINE;MARSHALL, GAYLE;SAM, MEHRAN |