| 摘要 |
Chemical agents which are inhibitors or activators of a protein whose expression affects a phenotypic characteristic of the cell, especially a cultural or morphological characteristic, can be identified by their more pronounced effect on cells producing higher, usually non-naturally occurring, levels of the protein, than on cells producing little or none of the protein. Such chemical agents are used to inhibit or activate a protein in a cell. By this method, tamoxifen is used to inhibit PKC activity in a cell.
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