发明名称 |
METHOD OF SCREENING REMEDY FOR HEART DISEASE AND MEDICINAL COMPOSITION FOR TREATING HEART DISEASE |
摘要 |
<p>A method for screening a substance that inhibits the onset of anti-cardiac troponin I autoantibody-related disease, a pharmaceutical composition and a base material for therapy of cardiac disease that contains the substance obtained by aforesaid method thereof, a therapeutic apparatus that removes anti-troponin I autoantibody for aforesaid antibody related disease, a method of making an animal model for evaluating cardiac disease characterized by administrating anti-cardiac troponin I antibody, a method of selection of a therapeutic substance for cardiac disease characterized by using aforesaid animals, and a diagnosis of dilated cardiomyopathy characterized by measuring anti-cardiac troponin I autoantibody. An apparatus of the present invention that removes anti-cardiac troponin I antibody and a pharmaceutical composition for therapy of the antibody related disease may be useful for a therapy and/or prevention of cardiac disease.</p> |
申请公布号 |
EP1619498(A2) |
申请公布日期 |
2006.01.25 |
申请号 |
EP20040727715 |
申请日期 |
2004.04.15 |
申请人 |
ONO PHARMACEUTICAL CO., LTD.;HONJO, TASUKU |
发明人 |
HONJO, TASUKU;OKAZAKI, TAKU |
分类号 |
A61K;A61K38/17;A61K45/00;A61P9/00;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/564;(IPC1-7):G01N33/50 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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