发明名称 Novel compounds, their use and preparation.
摘要 The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I). The invention also relates to (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride and a process for preparing the same. Another object of the present invention is a compound of the formula (I). Another object of the present invention is a method for the treatment or prophylaxis of a serotonin-related disorder, comprising administering to a subject in need thereof an effective amount of the compound above; as well as the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
申请公布号 ZA200409277(B) 申请公布日期 2006.01.25
申请号 ZA20040009277 申请日期 2004.11.18
申请人 BIOVITRUM AB. 发明人 BJOERN NILSSON;ERIK RINGBERG;MATTIAS JOENSSON;BIRGER SJOEBERG
分类号 A61K;A61P;C07D 主分类号 A61K
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