发明名称 Antioxidants, preparation methods and uses
摘要 The invention concerns compounds of general formula (I) (wherein R and R' represent an alkyl radical or an aryl group and R'' is hydrogen or a CO-R<SUP>1 </SUP>group wherein R<SUP>1 </SUP>is an alkyl radical or an aryl group; and the dimers formed by the disulphide bond from one and/or the other of the two sulphur atoms of the compounds of general formula (I); and the corresponding thiazolidin forms), the methods for preparing them and uses thereof. More particularly, it concerns the use of said compounds as antioxidant agents, in particular for preparing medicines designed to increase the intracellular and/or extracellular level of glutathione (GSH).
申请公布号 US6989372(B1) 申请公布日期 2006.01.24
申请号 US20010980291 申请日期 2001.11.27
申请人 COMMISSARIAT A L'ENGERGIE ATOMIQUE 发明人 OIRY JOEL;PUY JEAN-YVES;IMBACH JEAN-LOUIS;CLAYETTE PASCAL;FRETIER PHILIPPE
分类号 A61K31/265;C07D277/04;A61K8/00;A61K8/44;A61K8/46;A61K8/49;A61K8/60;A61K31/185;A61K31/404;A61K31/426;A61K31/52;A61K31/551;A61K31/662;A61K31/7072;A61K31/708;A61K45/00;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P17/00;A61P25/00;A61P27/02;A61P27/12;A61P27/16;A61P31/04;A61P31/12;A61P31/18;A61P33/00;A61P35/00;A61P37/02;A61P39/02;A61P43/00;A61Q5/00;A61Q5/04;A61Q5/06;A61Q19/00;A61Q19/08;C07C323/41;C07C327/30;C07C327/34;C07C329/06;C07K5/08;C09K15/28 主分类号 A61K31/265
代理机构 代理人
主权项
地址