发明名称 |
Method of treating cancer |
摘要 |
The present invention relates to methods of treating cancer using a combination of a compound which is an antineoplastic agent and a compound which is a inhibitor of prenyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at lest two therapeutic agents selected from a group consisting of a compound which is an antineoplastic agent and a compound which is an inhibitor or prenyl-protein transferase. The invention also relates to methods of preparing such compositions.
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申请公布号 |
US6989383(B1) |
申请公布日期 |
2006.01.24 |
申请号 |
US20000445054 |
申请日期 |
2000.03.27 |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
ROSEN NEAL;SEPP-LORENZINO LAURA;MOASSER MARK M.;OLIFF ALLEN I.;GIBBS JACKSON B.;KOHL NANCY;GRAHAM SAMUEL L.;PRENDERGAST GEORGE C. |
分类号 |
A61K31/495;C07D233/64;A61K31/198;A61K31/223;A61K31/335;A61K31/34;A61K31/35;A61K31/4178;A61K31/4439;A61K31/496;A61K31/497;A61K31/50;A61K31/506;A61K35/00;A61K41/00;A61K45/06;A61P43/00;C07C323/25;C07D241/04;C07D307/33;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D403/06;C07D403/10;C07D403/12 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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