摘要 |
The present invention provides a novel constitutive nitric oxide synthase (NOS) that utilizes both <SMALLCAPS>L</SMALLCAPS>-arginine and arginine-rich peptides, oligopeptides or proteins, e.g., bradykinin (BK), as substrates in the synthesis of nitric oxide (NO). Also provided are methods of controlling, regulating or modulating NO synthesis in a subject.
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