摘要 |
Two (or more), -component, body-implantable, absorbable, biocompatible, putty, and non-putty hemostatic tamponades for use in surgery. Component 1 is a finely powdered bulking material, preferably less than 50 microns, e.g. the calcium, magnesium, aluminum, or barium salts of saturated or unsaturated carboxylic acids containing about 6 to 22 carbon atoms, hydroxyapatite, DBM, polyglycolide, polylactide, poldioxinones, polycaprolactones, absorbable glasses, gelatin, collagens, mono, and polysaccharides starches. Component 2, a dispersing vehicle, may be esters unsubstituted and N-substituted pyrrolidones of C<SUB>8</SUB>-C<SUB>18 </SUB>monohydric alcohols with C<SUB>2</SUB>-C<SUB>6 </SUB>aliphatic monocarboxylic acids; C<SUB>2</SUB>-C<SUB>18 </SUB>monohydric alcohols with polycarboxylic acids; C<SUB>8</SUB>-C<SUB>30 </SUB>monohydric alcohols; tocopherol and esters thereof with C<SUB>2</SUB>-C<SUB>10 </SUB>aliphatic monocarboxylic acids or polycarboxylic acids; absorbable 10-14C hydrocarbons; free carboxylic acids such as oleic, capric, and lauric; dialkyl ethers and ketones; alkyl aryl ethers and ketones, polyhydroxy compounds and esters and ethers thereof; (ethylene oxide/propylene oxide copolymers), oils e.g. olive oil, castor oil and triglycerides.
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