摘要 |
The invention provides a human NR2E1 which is associated with the cardiovascular diseases, dermatological diseases, endocrinological diseases, gastroenterological diseases, cancer, metabolic diseases, hematological diseases, inflammation, respiratory diseases, muscle skeleton diseases, neurological diseases and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, dermatological diseases, endocrinological diseases, gastroenterological diseases, cancer, metabolic diseases, hematological diseases, inflammation, respiratory diseases, muscle skeleton diseases, neurological diseases and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of NR2E1 as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |