发明名称 |
Tri-block copolymers for nanosphere-based drug delivery |
摘要 |
Biocompatible non-toxic triblock copolymers having an A-B-A structure wherein each A is a hydrophilic, biocompatible end block and the B middle block is a hydrophobic desaminotyrosyl tyrosine polycarbonate or polyarylate. The copolymers spontaneously self-assemble to form low critical aggregation concentration nanospheres having utility as delivery vehicles for hydrophobic biologically or pharmaceutically active compounds.
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申请公布号 |
US2006013882(A1) |
申请公布日期 |
2006.01.19 |
申请号 |
US20050191181 |
申请日期 |
2005.07.27 |
申请人 |
RUTGERS, THE STATE UNIVERSITY |
发明人 |
KOHN JOACHIM B.;DEVORE DAVID;SHEIHET LARISA;DUBIN ROBERT |
分类号 |
A61K9/14;A61K47/48;C08G63/48;C08G69/44;C12N15/88 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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