PROCESS FOR THE PREPARATION OF 4,4-DIFLUORO-3-OXOBUTANOIC ACID ESTERS

摘要

The present invention relates to a process for the preparation of a compound of the formula (I), wherein R is C_1-12 alkyl, by the contact of a compound of the general formula (II) , wherein R₁ and R₂ are each, independently, C_1-12 alkyl; or R₁ and R₂ join together with the nitrogen atom to which they are attached to form an alicyclic amine ring containing 4 to 7 carbon atoms or a morpholine ring, with an acetic acid ester of the general formula (III) CH₃COOR, wherein R is as defined under formula (I), in the presence of a base.