| 摘要 |
The invention relates to the use of a compound comprising the following amino acid sequence X<SUB>1</SUB>X<SUB>2</SUB>X<SUB>3</SUB>X<SUB>4</SUB>X<SUB>5</SUB>X<SUB>6</SUB>X<SUB>7</SUB>, wherein X1 is an amino acid, except of C, X<SUB>2</SUB> is an amino acid, except of C, X<SUB>3</SUB> is an amino acid, except of C, X<SUB>4</SUB> is an amino acid, except of C, X<SUB>5</SUB> is an amino acid, except of C, X<SUB>6</SUB> is not present or any amino acid, X<SUB>7</SUB> is not present or any amino acid, and wherein X<SUB>1</SUB>X<SUB>2</SUB>X<SUB>3</SUB>X<SUB>4</SUB>X<SUB>5</SUB>X<SUB>6</SUB> is not DAEFRH, said compound having a binding capacity to an antibody being specific for the natural N-terminal Aß42 sequence DAEFRH, and 5-mers thereof having a binding capacity to said antibody being specific for the natural N-terminal Aß42 sequence DAEFRH, for the preparation of a vac- cine for Alzheimer's disease. |
