发明名称 |
VIRUS-LIKE PARTICLES, METHODS OF PREPARATION, AND IMMONOGENIC COMPOSITIONS |
摘要 |
Briefly described, virus-like particles, methods of preparing virus-like particles, immunogenic compositions that include virus-like particles, and methods of liciting an immune response using immunogenic compositions that include virus-like particles are described herein. A virus-like particle (VLP) can include a viral core protein that can self assemble into the VLP core and at least one viral surface envelope glycoprotein expressed on the surface of the VLP. The viral protein and the viral surface envelope glycoprotein are from different viruses. Another VLP can include a viral core protein that can self assemble into a VLP core; at least one viral surface envelope glycoprotein expressed on the surface of the VLP; and at least one adjuvant molecule expressed on the surface of the VLP. |
申请公布号 |
WO2004042001(A3) |
申请公布日期 |
2006.01.19 |
申请号 |
WO2003US15930 |
申请日期 |
2003.05.19 |
申请人 |
EMORY UNIVERSITY;COMPANS, RICHARD, W.;YANG, CHINGLAI;YAO, QIZHI;KANG, SANG-MOO |
发明人 |
COMPANS, RICHARD, W.;YANG, CHINGLAI;YAO, QIZHI;KANG, SANG-MOO |
分类号 |
C07K14/15;C07K14/16;C12N7/04;(IPC1-7):A61K39/12 |
主分类号 |
C07K14/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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