GENETISCH MANIPULIERTE ZELLEN DIE KNOCHENMORPHOGENESEPROTEINEN EXPRIMIEREN
摘要
The present invention describes methods of producing cell lines which express recombinant DNA encoding bone morphogenetic proteins (BMP). The cell lines are capable of being implanted in order to enhance the regeneration of tissues through both autocrine and paracrine effects. The cells may further contain DNA encoding receptor proteins which are able to bind to BMPs or enhance or regulate BMP activity.
申请公布号
AT314390(T)
申请公布日期
2006.01.15
申请号
AT19980945924T
申请日期
1998.09.04
申请人
GENETICS INSTITUTE, LLC;YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM
发明人
MOUTSATSOS, IOANNIS;GAZIT, DAN;ZILBERMAN, YORAM;TURGEMAN, GADI