| 摘要 |
A method for controlling the spacing, timing and degree of gene expression that includes selecting a target mRNA, obtaining siRNA corresponding to the target mRNA, modifying the siRNA with a photo-labile group to inhibit RNA interference, introducing the modified siRNA into a cell, and selectively irradiating the cell with light having a predetermined wavelength. A modified siRNA capable modulating gene expression that includes an siRNA that targets a predetermined complementary mRNA and at least one photo-labile group attached to said siRNA.
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