发明名称 |
Process for manufacturing of enantiomerically pure 3-hydroxy-3-phenyl-propylamin |
摘要 |
The present invention relates to an improved process for preparing enantiomerically pure 3-hydroxy-3-phenyl-propylamines on an industrial scale using asymmetrical hydrogenation as a key step and optionally a special sequence of subsequent steps, using a catalyst system consisting of rhodium and chiral 4-(dicyclohexylphosphino)-2-(diphenyl-phosphino-methyl)-N-methyl-aminocarbonyl-pyrrolidine.
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申请公布号 |
US2006009533(A1) |
申请公布日期 |
2006.01.12 |
申请号 |
US20050174086 |
申请日期 |
2005.06.30 |
申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
BAUMGARTEN WOLFGANG;SCHIFFERS ROBERT |
分类号 |
A61K31/138 |
主分类号 |
A61K31/138 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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