| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new RNA antisense compound which inhibits the action of telomerase and is effective for treating diseases in which the telomerase participates. <P>SOLUTION: A compound represented by the general formula: E1-B1-B2-B3-B4-E2 (I) (E1 is a group represented by formula: R1-, or the like; E2 is a group represented by formula: -B7-R2, or the like; B4, B5 and B8 are each identically or differently T<SP>p</SP>or the like; B1, B2, B3 and B12 are each identically or differentially G<SP>p</SP>or the like; B16 represented by formula: C<SP>p</SP>or the like; B6, B10, B14 and B18 are each identically or differently A<SP>p</SP>or the like), and a physiologically acceptable salt thereof. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
