发明名称 |
ACETYL CoA CARBOXYLASE SPLICE VARIANT AND USES THEREOF |
摘要 |
<p>The present invention relates to an isolated nucleic acid molecule comprising a nucleotide sequence that encodes an acetyl CoA carboxylase 2 (ACC2) splice variant. It also relates the corresponding polypeptide encoded by said nucleic acid and to methods of identifying a compound potentially useful for treating diseases or disorders associated with impaired ability to oxidise fatty acids, which comprises assaying the compound for its ability to modulate the activity or amount of a ACC2 splice variant complex or a complex thereof.</p> |
申请公布号 |
WO2006004549(A1) |
申请公布日期 |
2006.01.12 |
申请号 |
WO2005SE01121 |
申请日期 |
2005.07.06 |
申请人 |
ASTRAZENECA AB;CLAPHAM, JOHN;CORNELIUSSEN, BRIT;HALLEN, STEFAN |
发明人 |
CLAPHAM, JOHN;CORNELIUSSEN, BRIT;HALLEN, STEFAN |
分类号 |
C07K16/40;C12N9/00;C12Q1/68;(IPC1-7):C12N9/00;A61P3/04;A61P3/10;G01N33/573 |
主分类号 |
C07K16/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|