发明名称 ANTISENSE MODULATION OF PTP1B EXPRESSION
摘要 Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
申请公布号 WO2004071407(A3) 申请公布日期 2006.01.12
申请号 WO2004US02003 申请日期 2004.02.06
申请人 ISIS PHARMACEUTICALS, INC.;BHANOT, SANJAY;COWSERT, LEX, M.;WYATT, JACQUELINE, R.;FREIER, SUSAN, M.;MONIA, BRETT, P.;BUTLER, MADELINE, M.;MCKAY, ROBERT;DOBIE, KENNETH, W. 发明人 BHANOT, SANJAY;COWSERT, LEX, M.;WYATT, JACQUELINE, R.;FREIER, SUSAN, M.;MONIA, BRETT, P.;BUTLER, MADELINE, M.;MCKAY, ROBERT;DOBIE, KENNETH, W.
分类号 A61K;A61K38/00;A61K48/00;C12N5/02;C12N15/113 主分类号 A61K
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