BESTIMMUNG EINES MIDREGIONALEN PROADRENOMEDULLIN-TEILPEPTIDS IN EINER BIOLOGISCHEN FLÜSSIGKEIT ZU DIAGNOSTISCHEN ZWECKEN SOWIE IMMUNOASSAYS FÜR DIE DURCHFÜHRUNG EINER SOLCHEN BESTIMMUNG

摘要

Method for the determination of adrenomedullin immunoreactivity in biological fluids for diagnostic purposes, in particular in sepsis, cardiac and cancer diagnosis, in which the midregional partial peptide (mid-proAM; SEQ ID NO:3) of proadrenomedullin, which comprises the amino acids (45-92) of the complete preproadrenomedullin (pre-proAM; SEQ ID NO:1), is measured in particular by means of an immunoassay which operates with at least one labelled antibody which specifically recognizes a sequence of mid-proAM.