ENANTIOMERICALLY PURE ATOMOXETINE AND TOMOXETINE MANDELATE

摘要

The present invention provides enantiomerically pure (R)-(-)-tomoxetine (S)- (+)-mandelate and atomoxetine HCI. The present invention further provides enantiomerically pure (R)-(-)-tomoxetine (S)-(+)-mandelate prepared from racemic 5 tomoxetine. The present invention also provides enantiomerically pure atomoxetine HCI prepared from (R)-(-)-tomoxetine (S)-(+)-mandelate.