发明名称 |
ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS |
摘要 |
<p>Certain novel N-acylated spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.</p> |
申请公布号 |
EP1613601(A2) |
申请公布日期 |
2006.01.11 |
申请号 |
EP20040749540 |
申请日期 |
2004.03.31 |
申请人 |
MERCK & CO. INC. |
发明人 |
GUO, LIANGQIN;HE, SHUWEN;JIAN, TIANYING;LAI, YINGJIE;LIU, JIAN;NARGUND, RAVI, P.;SEBHAT, IYASSU, K.;UJJAINWALLA, FEROZE;YE, ZHIXIONG;YOUNG, JONATHAN, R. |
分类号 |
A61K31/445;A61K31/438;C07D221/20;C07D401/06;C07D401/14;C07D471/10;C07D491/10;(IPC1-7):C07D221/20 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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