| 发明名称 |
INTERGENIC REGIONS AS INSERTION SITES IN THE GENOME OF MODIFIED VACCINIA VIRUS ANKARA (MVA) |
| 摘要 |
<p>The present invention relates to a recombinant poxvirus vector capable of expressing two or more homologous, foreign sequences, which derive from different variants of a microorganism, and which have a homology of 50% or above. The invention further relates to a method for preparing such recombinant poxvirus and the use of such recombinant poxvirus as medicament or vaccine. Additionally, a method for affecting preferably inducing an immune response in a living animal, including a human, is provided.</p> |
| 申请公布号 |
EP1407033(B1) |
申请公布日期 |
2006.01.11 |
| 申请号 |
EP20030752741 |
申请日期 |
2003.05.14 |
| 申请人 |
BAVARIAN NORDIC A/S |
发明人 |
HOWLEY, PAUL;LEYRER, SONJA |
| 分类号 |
C12N15/09;C12N15/863;A61K31/70;A61K35/36;A61K39/12;A61K39/21;A61K39/285;A61K39/29;A61K39/39;A61P1/16;A61P31/12;A61P31/14;A61P31/18;A61P31/20;A61P35/00;C07K14/07;C07K14/16;C07K14/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12P21/02;C12Q1/68;C12Q1/70 |
主分类号 |
C12N15/09 |
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