| 发明名称 |
Use of FXR ligands |
| 摘要 |
The present invention includes nuclear receptor heterodimer and nuclear receptor-coactivator peptide assays for identifying ligands for nuclear receptors, utilizing scintillation proximity and fluorescence resonance energy transfer (FRET), and methods of using identified ligands.
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| 申请公布号 |
US6984650(B2) |
申请公布日期 |
2006.01.10 |
| 申请号 |
US20030637190 |
申请日期 |
2003.08.08 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
HAFFNER CURT DALE;MALONEY PATRICK REED;WILLSON TIMOTHY MARK;BLANCHARD STEVEN GERARD;KLIEWER STEVEN A.;LEHMANN JURGEN M.;PARKS DEREK JAMES;STIMMEL JULIE BETH |
| 分类号 |
A61K31/415;G01N33/50;A61K31/42;A61K45/00;A61P1/16;A61P3/04;A61P9/02;A61P9/10;C07D261/08;G01N33/15;G01N33/542;G01N33/566;G01N33/68;G01N37/00 |
主分类号 |
A61K31/415 |
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