发明名称 |
Mitochondrially targeted antioxidants |
摘要 |
The invention provides mitochondrially targeted antioxidant compounds comprising a lipophilic cation moiety covalently coupled to an antioxidant moiety which is either a superoxide dismutase (SOD) mimetic or a glutathione peroxidase mimetic. These compounds can be used to treat patients who would benefit from the reduction of oxidative stress.
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申请公布号 |
US6984636(B2) |
申请公布日期 |
2006.01.10 |
申请号 |
US20020217022 |
申请日期 |
2002.08.12 |
申请人 |
UNIVERSITY OF OTAGO |
发明人 |
MURPHY MICHAEL P.;SMITH ROBIN A. J. |
分类号 |
A61K31/555;C07D293/06;A61K31/662;A61K31/70;A61K47/48;A61P3/10;A61P9/00;A61P25/00;A61P25/16;A61P29/00;A61P37/06;A61P39/06;C07D293/12;C07D487/22;C07F9/547;C07F9/58;C07F9/6539;C07F13/00 |
主分类号 |
A61K31/555 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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