发明名称 |
Adhesion deficient isolate of Flavobacterium columnare against columnaris disease |
摘要 |
A safe and effective live vaccine against Flavobacterium columnare of fish was created through the induction of an adhesion deficient isolate of Flavobacterium columnare using a beta-lactam antibiotic (ampicillin). Single immersion exposure of fish stimulated acquired immunity against virulent F. columnare infection.
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申请公布号 |
US6984388(B1) |
申请公布日期 |
2006.01.10 |
申请号 |
US20040774248 |
申请日期 |
2004.02.06 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE |
发明人 |
BADER JOEL A.;SHOEMAKER CRAIG A.;KLESIUS PHILLIP H. |
分类号 |
A61K39/02 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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