| 摘要 |
A pharmaceutical preparation comprising a solution which contains as the active ingredient a substance selected from the group consisting of arginine amides represented by the general formula (I), salts thereof, and hydrates of both in a concentration of 1 to about 10mg/mL (with the proviso that the solution must contain at least water) and is packed in a container having a capacity of about 1 to about 20 mL: (I) [wherein R1 is (2R, 4R)-4-alkyl-2- carboxypiperidino; and R2 is phenyl or a residue of a fused polycyclic compound, and R2 may have one or more substituents selected from among lower alkyl, lower alkoxy, and amino groups susbstituted with lower alkyl groups, with the provisos that the residue of a fused polycyclic compound bears a benzene ring and the benzene ring is bonded to the sulfonyl sulfur in the general formula (I) and fused with other rings including heterocycles and that the total number of ring-constituting carbon atoms of the residue is 7 to 14]. The pharmaceutical preparations and pharmaceutical compositions of the invention have advantages of high convenience and safety in medical service, good storage stability, and easy and simple producibility.
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