IBUPROFEN NARCOTIC COMPOSITION AND METHOD FOR MAKING SAME

摘要

In a method of making a pharmaceutical composition, ibuprofen, in a concentration of between 10% and 84%, a narcotic analgesic (102) and at least one excipient (104) are mixed in a dry powder phase (108). The ibuprofen, the narcotic analgesic (102) and the at least one excipient (104) are compacted to form a substantially dry compact material (112), also referred to as a compact. The dry compact material (112) is milled, or otherwise sized, to form a plurality of dry granules (116). The dry granules (116) are compressed to form a plurality of tablets (132).