发明名称 |
Sigma-2 receptor agonists and their use in the treatment of HIV infection |
摘要 |
The present invention relates to sigma-2 receptor agonists and their use in the treatment of immunodeficiency virus infections, especially human immunodeficiency virus (HIV) infections. The invention particularly relates to sigma-2 agonists, especially CB-184 and its analogues, that decrease cellular production of sphingomyelin when provided to recipient cells, and inhibit HIV replication.
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申请公布号 |
US2006004036(A1) |
申请公布日期 |
2006.01.05 |
申请号 |
US20050181797 |
申请日期 |
2005.07.15 |
申请人 |
THE UNITED STATES OF AMERICA, PER SECY. DHHS, NIH |
发明人 |
BOWEN WAYNE D.;CRAWFORD KEITH W.;HILDRETH JAMES E. |
分类号 |
A61K31/485;A61K;A61K31/00;A61K31/435;A61K31/44 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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