发明名称 MEDICINAL COMPOSITION FOR PROMOTING GLUCOSE-RESPONSIVE INSULIN SECRETION
摘要 <p>A product in the field of medicines. More specifically speaking, a medicine characterized in that a compound having an effect of inhibiting hedgehog signaling is applied as the active ingredient to diseases for the prevention and treatment of which glucose-responsive insulin secretion should be promoted. By administering the hedgehog signaling inhibitor as described above, insulin secretion by pancreatic Langerhans ß-cells is promoted so that advantageous preventive and therapeutic effects can be exerted on various disease relating to blood sugar control failures such as diabetes.</p>
申请公布号 WO2006001471(A1) 申请公布日期 2006.01.05
申请号 WO2005JP11898 申请日期 2005.06.29
申请人 THE UNIVERSITY OF TOKYO;SAKAI, JURO;KODAMA, TATSUHIKO;MAGOURI, KENTA 发明人 SAKAI, JURO;KODAMA, TATSUHIKO;MAGOURI, KENTA
分类号 A61K45/00;A61K31/4355;A61K31/497;A61K31/5685;A61K31/685;A61P3/04;A61P3/06;A61P3/10;A61P43/00 主分类号 A61K45/00
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