发明名称 |
MEDICINAL COMPOSITION FOR PROMOTING GLUCOSE-RESPONSIVE INSULIN SECRETION |
摘要 |
<p>A product in the field of medicines. More specifically speaking, a medicine characterized in that a compound having an effect of inhibiting hedgehog signaling is applied as the active ingredient to diseases for the prevention and treatment of which glucose-responsive insulin secretion should be promoted. By administering the hedgehog signaling inhibitor as described above, insulin secretion by pancreatic Langerhans ß-cells is promoted so that advantageous preventive and therapeutic effects can be exerted on various disease relating to blood sugar control failures such as diabetes.</p> |
申请公布号 |
WO2006001471(A1) |
申请公布日期 |
2006.01.05 |
申请号 |
WO2005JP11898 |
申请日期 |
2005.06.29 |
申请人 |
THE UNIVERSITY OF TOKYO;SAKAI, JURO;KODAMA, TATSUHIKO;MAGOURI, KENTA |
发明人 |
SAKAI, JURO;KODAMA, TATSUHIKO;MAGOURI, KENTA |
分类号 |
A61K45/00;A61K31/4355;A61K31/497;A61K31/5685;A61K31/685;A61P3/04;A61P3/06;A61P3/10;A61P43/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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