| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a cough/cold tablet formulation with controlled release and absorption assuring a predetermined release rate and effective tablet formulation by accurately controlling release of a plurality of active ingredients. <P>SOLUTION: The cough/cold tablet formulation with the controlled release and absorption comprises a tablet core containing the plurality of active ingredients, in particular an antihistamine, a decongestant and a cough suppresant, together with a pharmaceutically acceptable excipient. A specific permeable membrane surrounds the core and contains at least one of the active ingredients present in the core, wherein the membrane contains a major amount of a component which is impermeable to each of the active ingredients and a minor amount of a component which, when the tablet is placed in an aqueous environment, permits the release of each of the active ingredients and the pharmaceutically acceptable excipient present in the core, at a rate allowing controlled release and absorption thereof. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |
