MINIPROTEIN LIGANDS AND OTHER POLYPEPTIDES AND METHODS FOR MAKING AND USING SAME
摘要
Disclosed are polypeptides which include an amino acid sequence corresponding to CCXXXCKEGXXC (SEQ ID NO:1). Also disclosed are methods for inhibiting the activity of a flavivirus or other virus by contacting the virus with a miniprotein ligand under conditions effective for the miniprotein ligand to bind to the virus. Methods for detecting a flavivirus or other virus in a sample by contacting the sample with a miniprotein ligand and determining whether the miniprotein ligand is bound to a flavivirus or other virus as also disclosed, as are methods of assessing a compound's usefulness in inhibiting the activity of a flavivirus or other virus.
申请公布号
WO03095477(A3)
申请公布日期
2006.01.05
申请号
WO2003US08150
申请日期
2003.03.17
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;FOX, ROBERT, O.;BARRETT, ALAN, D.;FAN, XIUZHEN;HOLBROOK, MICHAEL, R.
发明人
FOX, ROBERT, O.;BARRETT, ALAN, D.;FAN, XIUZHEN;HOLBROOK, MICHAEL, R.