| 发明名称 |
ORGAN-FORMING METHOD |
| 摘要 |
<p>A method for forming an organ and/or tissue from undifferentiated cells derived from a vertebrate animal in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid X receptor ligand (e.g., a retinoic acid X receptor agonist or antagonist), and a method for forming a pancreas from undifferentiated cells derived from a vertebrate animal in vitro or a method for forming a tissue having morphology and function of a pancreas from undifferentiated cells derived from a vertebrate in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid receptor ligand, together with activin, that does not substantially bind to the retinoic acid receptor subtype ³.</p> |
| 申请公布号 |
EP1612264(A1) |
申请公布日期 |
2006.01.04 |
| 申请号 |
EP20040721319 |
申请日期 |
2004.03.17 |
| 申请人 |
RESEARCH FOUNDATION ITSUU LABORATORY |
发明人 |
ASASHIMA, MAKOTO;HAMAZAKI, TATSUO;KAGECHIKA, HIROYUKI;SHUDO, KOICHI |
| 分类号 |
C12N5/00;(IPC1-7):C12N5/06 |
主分类号 |
C12N5/00 |
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