发明名称 Pyrrolotriazine inhibitors of kinases
摘要 The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
申请公布号 US6982265(B1) 申请公布日期 2006.01.03
申请号 US20000573829 申请日期 2000.05.18
申请人 BRISTOL MYERS SQUIBB COMPANY 发明人 HUNT JOHN T.;BHIDE RAJEEV S.;BORZILLERI ROBERT MICHAEL;QIAN LIGANG
分类号 A61P27/02;C07D487/04 主分类号 A61P27/02
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