发明名称 |
Compositions and methods modulating variola and vaccinia virus |
摘要 |
Antibodies directed to SPICE and VCP which may be used for detection, prevention, and treatment of variola virus or vaccinia virus are provided. Recombinant SPICE and VCP proteins are also provided which are used for enhancing the immune response to variola or vaccinia virus and modulating of complement activation. Methods and kits for detecting nucleic acid sequences encoding SPICE and VCP are also provided.
|
申请公布号 |
US6982156(B2) |
申请公布日期 |
2006.01.03 |
申请号 |
US20030441624 |
申请日期 |
2003.05.20 |
申请人 |
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
ROSENGARD ARIELLA M. |
分类号 |
A61K39/42;A61K38/00;A61K39/00;A61K39/395;C07H21/04;C07K14/07;C07K16/08;C12Q1/70;G01N33/569 |
主分类号 |
A61K39/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|