发明名称 |
NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH |
摘要 |
<p>Disclosed are (2S)-2-{1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric, Potassium-(2S)-2-{1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyrate, monohydrate and its Form I polymorph. Also disclosed are compositions of the described forms, kits including the described forms, and methods of using the described forms for the treatment diseases or disorders where the use of a neutral endopeptidase inhibitor is indicated, including cardiovascular diseases and conditions.</p> |
申请公布号 |
WO2005123702(A1) |
申请公布日期 |
2005.12.29 |
申请号 |
WO2005IB01911 |
申请日期 |
2005.06.03 |
申请人 |
PFIZER LIMITED;DACK, KEVIN, NEIL;GYMER, GEOFFREY, EDWARD;PFIZER INC. |
发明人 |
DACK, KEVIN, NEIL;GYMER, GEOFFREY, EDWARD |
分类号 |
A61K31/421;A61P9/12;C07D263/32;(IPC1-7):C07D263/32 |
主分类号 |
A61K31/421 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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