发明名称 NEUTRAL ENDOPEPTIDASE INHIBITOR POLYMORPH
摘要 <p>Disclosed are (2S)-2-{1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric, Potassium-(2S)-2-{1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyrate, monohydrate and its Form I polymorph. Also disclosed are compositions of the described forms, kits including the described forms, and methods of using the described forms for the treatment diseases or disorders where the use of a neutral endopeptidase inhibitor is indicated, including cardiovascular diseases and conditions.</p>
申请公布号 WO2005123702(A1) 申请公布日期 2005.12.29
申请号 WO2005IB01911 申请日期 2005.06.03
申请人 PFIZER LIMITED;DACK, KEVIN, NEIL;GYMER, GEOFFREY, EDWARD;PFIZER INC. 发明人 DACK, KEVIN, NEIL;GYMER, GEOFFREY, EDWARD
分类号 A61K31/421;A61P9/12;C07D263/32;(IPC1-7):C07D263/32 主分类号 A61K31/421
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