发明名称 |
Water-soluble polymeric bone-targeting drug delivery system |
摘要 |
The present invention provides bone-targeting polymeric drug delivery systems based on HPMA and related copolymers and methods of making thereof. The water-soluble bone-targeting polymeric conjugates of the present invention comprise water-soluble copolymer backbones (P) which are linked, via a first spacer (S<SUB>1</SUB>), with a bone-related therapeutic agents or drug (D) and, via a second spacer (S<SUB>2</SUB>), with a bone-targeting moiety (T).
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申请公布号 |
US2005287114(A1) |
申请公布日期 |
2005.12.29 |
申请号 |
US20050150865 |
申请日期 |
2005.06.10 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
WANG DONG;MILLER SCOTT C.;KOPECKOVA PAVLA;KOPECEK JINDRICH |
分类号 |
A61K;A61K31/785;A61K38/06;A61K38/08;A61K47/48;C07C237/20;C07C237/26;(IPC1-7):A61K38/08 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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