Removal of bacterial DNA from therapeutic fluid formulations

摘要

This invention discloses methods and devices useful for eliminating or reducing the adverse effects associated with the use of a variety of therapeutic fluids. It is proposed herein that the source of such side effects (e.g. fever and septic shock) is the oligonucleotides present in the fluid and that using the ultrafiltration and adsorption methods and devices disclosed in the invention one can minimize the risk of these adverse effects often associated with dialysis treatment.