| 发明名称 |
Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria |
| 摘要 |
The present invention relates in general to spectroscopic methods for direct observation of membrane dynamics in living cells and their application to drug discovery methods. More particularly, the present invention relates to methods for observing iron transport activity in the outer membrane of living bacteria and more specifically to a ligand-specific opening of a gated-porin channel in the outer membrane of a living bacteria.
|
| 申请公布号 |
US2005287070(A1) |
申请公布日期 |
2005.12.29 |
| 申请号 |
US20050203712 |
申请日期 |
2005.08.15 |
| 申请人 |
KLEBBA PHILLIP F;NEWTON SALETE M |
发明人 |
KLEBBA PHILLIP F.;NEWTON SALETE M. |
| 分类号 |
C12Q1/02;A61K9/00;A61K49/00;A61K49/20;C12N1/20;C12Q1/04;C12Q1/18;G01N33/58;G01N33/68;(IPC1-7):A61K49/00 |
主分类号 |
C12Q1/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
