发明名称 |
METHODS OF INHIBITING INFLAMMATION |
摘要 |
The invention provides for microsomal triglyceride transfer protein inhibitors and methods of inhibiting CD-1 mediated inflammation or immune function and inhibiting association of MTP and CD-1, with said inhibitors. Other methods disclosed include reducing lipidation of a CD1 molecule in a cell and increasing anti-tumor immunosurveillance with administration of an MTP inhibitor. |
申请公布号 |
WO2005102380(A3) |
申请公布日期 |
2005.12.29 |
申请号 |
WO2005US04059 |
申请日期 |
2005.02.09 |
申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;BLUMBERG, RICHARD, S. |
发明人 |
BLUMBERG, RICHARD, S. |
分类号 |
A61K31/4184;A61K31/422;A61K31/427;A61K31/445;A61K31/454;A61K31/4545;A61K31/506;A61K38/17 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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