发明名称 BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES
摘要 This invention relates to compounds of the formula (I): wherein R<1>, R<2>, R<3>, A and m are each as described herein or a pharmaceutically acceptable salt or solvate thereof, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by 5-HT4 receptor activity such as, but not limited to, gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageral disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorders such as cardiac failure and heart arrhythmia, diabetes and apnea syndrome.
申请公布号 WO2005123718(A2) 申请公布日期 2005.12.29
申请号 WO2005IB01825 申请日期 2005.06.01
申请人 PFIZER JAPAN INC.;ANDO, KOJI;IGUCHI, SATORU;MURASE, NORIAKI;MURATA, YOSHINORI;NUMATA, TOYOHARU;SONE, HIROKI;UCHIDA, CHIKARA;UEKI, TATSUO;PFIZER INC., 发明人 ANDO, KOJI;IGUCHI, SATORU;MURASE, NORIAKI;MURATA, YOSHINORI;NUMATA, TOYOHARU;SONE, HIROKI;UCHIDA, CHIKARA;UEKI, TATSUO
分类号 A61K31/41;A61K31/4184;A61K31/4245;A61K31/433;A61K31/453;A61K31/454;A61P1/00;A61P1/04;A61P1/06;A61P3/10;A61P9/00;A61P25/00;A61P25/06;A61P25/28;C07D401/12;C07D401/14;C07D403/00;C07D403/14;C07D405/14;C07D413/14;C07D417/14 主分类号 A61K31/41
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