发明名称 |
Process for expression of foreign genes in methylotrophic bacteria through chromosomal integration |
摘要 |
Provided is a method for expressing an introduced gene or genes in a C1 metabolizing microorganism host wherein the gene(s) are integrated into the tig region of the chromosome. This method provides high level expression in a stable manner in which growth rate of the host strain is not highly affected and a selection marker is not required. The use of this method for expressing carotenoid biosynthetic genes and resulting production of canthaxanthin is also described.
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申请公布号 |
US2005287625(A1) |
申请公布日期 |
2005.12.29 |
申请号 |
US20050070080 |
申请日期 |
2005.03.02 |
申请人 |
MILLER EDWARD S JR;YE RICK W |
发明人 |
MILLER EDWARD S.JR.;YE RICK W. |
分类号 |
C12N1/20;C12N1/21;C12N9/00;C12N15/74;C12P21/00;C12P23/00;C12R1/26;(IPC1-7):C12P23/00 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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