发明名称 |
USE |
摘要 |
The present invention provides the use of a DNA molecule encoding an antigen (and in particular encoding a bacteria or virus glycoprotein, preferably a rhabdovirus glycoprotein) which is expressed on the surface of a host cell, or variant, or a fragment thereof, in the manufacture of a medicament for use as a vaccine adjuvant or to enhance the immune stimulating properties or vaccination properties of a vaccine molecule, or to enhance the immune response to a vaccine molecule. A composition comprising said DNA molecule encoding an antigen which is expressed on the surface of a host cell, or variant, or a fragment thereof, and a vaccine molecule, is also provided. A further aspect of the present invention provides the use of said DNA molecule encoding an antigen which is expressed on the surface of a host cell, or variant, or a fragment thereof, in the manufacture of a composition which can improve or increase the elimination of other foreign DNA molecules from an organism. |
申请公布号 |
WO2005123121(A2) |
申请公布日期 |
2005.12.29 |
申请号 |
WO2005GB02472 |
申请日期 |
2005.06.22 |
申请人 |
FORINNOVA AS;NERLAND, AUDUN, HELGE;LORENZEN, NIELS;SOMMERSET, INGUNN;OWEN, DEBORAH, JANE |
发明人 |
NERLAND, AUDUN, HELGE;LORENZEN, NIELS;SOMMERSET, INGUNN |
分类号 |
A61K39/00;A61K39/12;A61K39/205;A61K39/39;C07K14/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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